Welcome to
The MEI Lab
Department of Molecular Pharmaceutics
A Molecular Pharmaceutics Lab
We Develop Drug & Gene Delivery Systems for Novel Immunotherapies
mRNA-LNPs (Photo Credit: the MEI Lab)
ImmunoEngineering
We specialize in engineering lipid-based nanoscale therapeutic carriers, such as liposomes & lipid nanoparticles (LNPs). We utilize LNPs as our therapeutic toolboxes to deliver RNA/DNA, modulating immune responses and achieving therapeutic benefits in various applications.
Our primary disease of interest includes:
Immunogenicity-control for AAV Gene Therapy
Immunogenic mRNA Cancer Vaccines
(Colon, Melanoma, Breast Cancer)Tolerogenic mRNA Vaccine Development
CAR-based Immuno-Cell Therapy
LNPs
MEI Lab-modified Cy5-eGFP-mRNA-LNPs in dendritic cells showing endosomal escape (Cy5-mRNA in megenta) from lysosomes (red/yellow), leading to highly efficient protein translation from mRNA encoding green fluorescent proteins (eGFP/green)
(Photo Credit: the MEI Lab | U.S. Patent Application No. 63/745,773, 2025)
We synthesize lipids and formulate mRNA-LNPs, studying their intracellular trafficking and downstream biological effects to develop precision RNA therapeutics.
Looking for PhD & Postdoc Training in Molecular Pharmaceutics or Biological Chemistry?
Join Us
at the University of Utah, SLC
A great place to study, work, and live
Why Utah?
US Top 10 by
NIH Research Funding
College of Pharmacy
State-of-theArt Research Infrastructure
World Class Medical Research Center
U of U Medical Campus
in Salt Lake City
Research Funding
